BoneXpert is a medical software device running on a Windows PC.
BoneXpert conforms to the European Community Directive for Medical Devices EC 1993/42, as indicated by the CE mark.
Caution: Not approved for clinical use in the USA.
The intended use of BoneXpert is to perform an autonomous determination of bone age and bone health index (BHI). The bone age determination can replace the conventional manual rating. The hand radiograph must be provided as a DICOM file.
BoneXpert is licensed through an annual license fee based on an estimate of the number of annual analyses made. A free trial period is offered for the BoneXpert Server and the Online version.
BoneXpert is licensed through an annual license fee based on an estimate of the number of annual analyses made. A free trial period is offered for the BoneXpert Server and Online version.
Performance
| Range of application | Bone age range | 0-19 years for boys and 0-18 years for girls (GP bone age ranges) |
| Ethnicities | Caucasian, African-American, Hispanic, and Asian in USA and Japan | |
| Disorders | Healthy children, short stature (e.g. Turner and GHD), pubertes praecox, tall stature, CAH, SHOX, Klinefelter | |
| Bone Age | Bone age scales | Greulich-Pyle (GP), Tanner-Whitehouse (TW2, TW3, TWJapan) and Fels |
| Bone age precision, SD | 0.00 years when rerating the same image 0.16 years or less when taking a new X-ray |
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| Bone age accuracy, SD | 0.63 years (GP bone age relative to average manual rater) 0.59 years (TW3 bone age, relative to an excellent rater) |
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| Bone age sensitivity to image quality | <0.20 years (95% conf) | |
| Accuracy of adult height prediction, SD | 3.3 cm (healthy Caucasian boys aged 10-15 years) 2.7 cm (healthy Caucasian girls aged 8-13 years) |
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| Bone Health Index | BHI precision SD | 1.4% at age 10 years |
| BHI sensitivity to image quality (accuracy) | <4.0% (95% conf) |