The US patent office has granted Visiana a patent for the invention of an image processing method.
A key element of BoneXpert is to locate each bone accurately as a first step in the bone age analysis. Visiana has invented a new method to locate a landmark, e.g. the tip of a bone. About 100 examples are needed for the machine learning method, which trains a decision tree to predict the location from a nearby image patch. The predictions from more than 300 patches are placed in a voting map, and the peak of votes yields the landmark location with subpixel accuracy. The figure shows the voting map for finding the tip of a distal phalanx.
The invention could also be useful in land vehicles and smartphones.
With the implementation of BoneXpert at the University Hospital in Innsbruck in Austria, there are now over 200 departments, who have licensed BoneXpert, each performing between 100 and 6000 analyses per year.
The driving force of this growth of the installed base is the BoneXpert Server Edition with its easy installation, easy maintenance, and excellent workflow
A study published in Journal of the Endocrine Society by Vogiatzi and Ross of Jefferson University Hospital in Philadelphia, followed 90 Klinefelter boys, half of which were treated with Oxandrolone – an anabolic steroid.
(Males have one X and one Y chromosome and females have two X chromosomes. Klinefelter boys have two X and one Y chromosome, i.e. XXY. The incidence Klinefelter Syndrome is 1 of 800 boys.)
Read more “Bone Health Index demonstrates relation to fractures in Klinefelter children”
Visiana held its BoneXpert webinar to explore the automation of the processes in radiology that is currently taking place in the UK.
Presenters were Professor Amaka Offiah, and Dr. Alistair Calder who presented their views and findings when using BoneXpert in the daily routine at Sheffield University Hospital and at Great Ormond Street Hospital in London.
The webinar was well-attended, and here are a some highlights.
Read more “Financial impacts of BoneXpert; Webinar highlights with Prof. Amaka Offiah and Dr. Alistair Calder”
In April, Kicky van Leeuwen et al presented the paper Artificial intelligence in radiology: 100 commercially available products and their scientific evidence. It got quite some attention, because it documents what many have suspected, namely, that most AI products lack sufficient publications.
Read more “BoneXpert – A mature AI product”
Visiana welcomes the South-Eastern Norway Regional Health Authority (Helse Sør Øst) as a BoneXpert customer. Helse Sør Øst includes Norway’s capital Oslo, and the authority provides health care for 56% of Norway’s population.
Around 50 hospitals in Scandinavia are performing more than 100 bone age analyses per year. With the addition of Helse Sør Øst, BoneXpert is licensed to all of these hospitals with the exception of 1 hospital in Norway, 2 in Sweden and 1 in Finland.
A new paper by Suma Uday et al reports the use of BoneXpert to study bone age and BHI in deprived Afghan children of age 1.5-2.5 y. This validates version 3 of BoneXpert, which extends the bone age range down to new-borns – the older version of BoneXpert was valid only down to 2.5 years.
Read more “BoneXpert validated in Afghan toddlers”
A study from Queen Fabiola Children’s University Hospital in Brussels on the accuracy of bone age has been published.
Read more “BoneXpert is accurate in Moroccan children”
Searching PubMed with “BoneXpert” yields 50 publications until the end of 2020.
Until 2017, there were 31 publications of which 18 were coauthored by Visiana.
In 2018-20, there were 19 publication, and none of the them were coauthored by Visiana, marking a shift towards independent validation studies.
30 of the 50 publications were on bone age, 5 were on adult height prediction and a surprisingly large number, 15, were on the Bone Health Index.
Explore the abstracts of these publications here: https://pubmed.ncbi.nlm.nih.gov/?term=bonexpert&filter=years.2009-2020