Bone age can be automatically measured from a child's hand X-ray by the BoneXpert software. BoneXpert delivers precise and standardised readings, thus overcoming the problem of considerable reader variability of manual ratings.
Leading paediatric radiology departments have integrated BoneXpert seamlessly in their workflow. This provides better input to the physician's diagnosis, gives more accurate adult height prediction, and more optimal treatment. In addition, clinics now have an improved workflow and treat patients quicker as bone age is provided by BoneXpert as soon as the X-ray is recorded.
Running on existing hardware and paid per analysis, BoneXpert is cost-effective from day one. Doctors are relieved from time-consuming manual ratings, leading to more time for patient care.
BoneXpert Core Values
Autonomous
BoneXpert is autonomous rather than just assisting. This level of ambition is crucial for delivering real value of AI, safely relieving the radiologist from tedious work. BoneXpert automatically rejects the image if the safe interpretation is not guaranteed.
Many of the radiologists using BoneXpert, are still looking at the hand image to check for signs of anatomical anomaly, and occasionally checking the bone age assessment.
Accurate
BoneXpert was trained on 30.000 X-rays, and its agreement with the average of six manual raters is excellent, with a mean absolute deviation of only 4.1 months.
BoneXpert has been validated across hospitals, modality brands and populations (Asian, Caucasian, Hispanic, African).
20 peer-reviewed publications document the clinical evaluation, including studies the of the accuracy of adult height prediction based on bone age.
Explained
BoneXpert explains the overall bone age as the averaging over the annotated bones, like a human rater would do.
For each bone, BoneXpert displays the boundary, which substantiates the analysis, e.g. the relative width of the epiphysis is a crucial maturity indicator.
A separate bone age value is given for the carpals, which are known to respond differently to sex steroids.
Validation of BoneXpert in India
BHI reference curves in 12 populations
Hand radiographs as a potential replacement for DXA in osteopenia screening
Auckland Radiology Group become the first private radiology clinic in New Zealand to adopt BoneXpert
External validation of commercial AI products
Ruby Hall Clinic uses BoneXpert software
Aerial view of Radiology AI in the Netherlands
Fracture study from Birmingham
Widespread use of BoneXpert in the United Kingdom
Swiss study compares two bone age algorithms
BoneXpert – the most widely used radiology AI in the Netherlands in 2022
BoneXpert knows its own limitation
New paper: How do radiologists use BoneXpert?
United States patent granted to Visiana
Over 200 hospitals have licensed BoneXpert
Bone Health Index demonstrates relation to fractures in Klinefelter children
Financial impacts of BoneXpert; Webinar highlights with Prof. Amaka Offiah and Dr. Alistair Calder
How well does Bone Health Index correlate with DXA?
BoneXpert – A mature AI product
Almost full house in Scandinavia
BoneXpert validated in Afghan toddlers
BoneXpert is accurate in Moroccan children
Celebrating 50 BoneXpert publications on PubMed
New Adult Height Predictor supports three ethnicities
What do PACS admins say about BoneXpert?
BoneXpert Online: Automated bone age in your browser
New bone age reference curves from Taiwan
Visiana expands and unveils new office space
New bone age reference curves from Mexico
Dutch paper on implementation of AI in radiology
BoneXpert – the most widespread AI radiology software in the Netherlands
Reduced use of bone age during Covid-19
BoneXpert in Chile
RSNA challenge boosts automated bone age ratings
BoneXpert version 3.0 released
BoneXpert in 135 hospitals
Hands-on AI
BoneXpert licensed to 100 hospitals
Special Focus Session on age assessment at ESPR 2017
BoneXpert licensed to 80 hospitals
Assessment of arthritis with BoneXpert
Automated bone age extended up to 19 years
The world’s first osteoporosis screening
BoneXpert licensed to 60 hospitals
Adult height Prediction Study in Paris
New Adult Height Predictor with growth path
The friendly co-existence of BoneXpert and image post-processing
BoneXpert licensed to 32 hospitals
Three new publications
Adult height prediction for short children
BoneXpert licensed to 16 hospitals
New thoughtful article in Radiology about CAD
How dangerous is it to eat a banana?
Three new publications
New validation study of BoneXpert in Academic Radiology
April 2010: Three new publications
Dr. David Martin receives the Jürgen-Bierich Prize for work on adult height prediction
New paper on Bone Health Index
Clinical Review of BoneXpert in JCEM
Bone Age Application Areas
Clinical Use
Installed in the radiology department and serving mainly paediatric endocrinology and orthopedics
Clinical Trials
Academic research or drug trials sponsored by pharmaceutical companies
Sports Medicine
Talent identification and prevention of injuries
Orthodontics
Planning the timing of treatment
Used by over 200 clinics
Testimonials
”Today, BoneXpert is an invaluable tool in our clinical practice.”
“The speed of reporting allows you to save hours of annual work for the radiologist specialist who can then be employed in other activities/reporting.”
"In addition to being an efficient and reliable programme, BoneXpert has also increased our awareness of bone health, especially in the transplanted children (mostly liver and kidneys)."
“With BoneXpert, we have a system that accurately measures trends in bone age.”
"We looked further at the films in which there was more than 12 months’ discrepancy between BoneXpert and the radiologist. There were 20 discrepancies. In 19 cases, BoneXpert was right."
“I'm happy to use it and would certainly recommend it to radiologists who have to read a substantial number of bone age studies.”
“Since we introduced it into our clinical service last year it has reduced the radiologists workload.”
“BoneXpert is also a useful tool for the less experienced radiologist and a way to teach manual rating.”
“BoneXpert integrates with our local PACS and has given us rapid turnaround and improved consistency. In fact, our radiologists have stopped doing bone ages manually now.”
“The Bone Health Index (BHI) can help us find a weaker bone structure at risk of fracture.”
“BoneXpert is and will remain a valuable assistant in my daily work.”
“As the software gives the automated assessment of each bone individually as well as a composite age, it is also easy for the referring doctor to read them.”
“The accuracy, objectiveness, and the advantage of standardized comparing of bone maturation in the follow-up is so important that we cannot practically imagine our practice without BoneXpert.”
“When I need a Bone Age, I send the child for the x-ray immediately, and even before they are back, we have the answer and, in a jiffy, a height prediction, too. We are doing far more bone ages than we expected.”
“The Bone Health Index (BHI) can help us find a weaker bone structure at risk of fracture.”
“In a short time, BoneXpert has become a valuable assistant in our daily work in our busy environment.”